Following section 6 of the Toxic Substances Control Act (TSCA), the U.S. Environmental Protection Agency (EPA) submitted a proposed adjustment to the unreasonable risk finding for 1-bromopropane (1-BP) for public comment.

According to the proposed revised risk determination, 1-BP is a completely chemical substance that provides an excessive risk of harm to human health under usage conditions. To ensure that the public is protected from irrational risks from chemicals in a way that is supported by science and the law, the 1-BP draught updated risk determination includes policy revisions that were released in June 2021.

1-BP is a volatile organic molecule that has many applications, including as a solvent in degreasing procedures, spray adhesives, and dry cleaning. Additionally, a wide range of consumer and business products, including aerosol degreasers, spot cleaners, and construction materials, include 1-BP. Acute and long-term dermal and inhalation exposures to 1-BP have been linked to harmful human health effects.

Separately, EPA is using a screening methodology to evaluate possible dangers from 1-BP's water and air routes. If there are concerns that were not considered in the risk assessment for 1-BP, they will be found using the EPA's screening method.

EPA is not applying the screening-level technique to this draught updated unreasonable risk conclusion while this analysis is in progress. If the findings indicate, there is an extra risk; EPA will decide whether the risk management strategy being considered for 1-BP will protect from these risks or whether a new risk review is necessary.

Be aware that EPA's actions today do not include any new scientific research on 1-BP. A decision of an unreasonable risk for 1-BP as a total chemical substance can be supported by the 1-BP risk evaluation's continued characterization of risks related to specific conditions of use. This information is also used to guide risk management.

Reference: https://www.epa.gov/chemicals-under-tsca/epa-releases-draft-revised-risk-determination-1-bromopropane-public-comment