The Office of Environmental Health Hazard Assessment (OEHHA) intends to list perfluorooctanoic acid (PFOA) and Perfluoro octane Sulfonic Acid (PFOS) as known to the state to beget cancer under the Coffer Drinking Water and Poisonous Enforcement Act of 1986 ( Proposition 65). This action is proposed by the “ Authoritative Bodies” listing medium. According to the National Toxicology Program (NTP 2020), PFOA was extensively used in manufacturing a variety of consumer products that included numerous nonstick operations, similar to apparel and cookware. PFOA is no longer produced in the US and its product and use worldwide was significantly elided with the 2019 ban of the emulsion under the Stockholm Convention on Persistent Organic Adulterants.

 Below conditions are used to list the chemicals under Prop-65 (Listing medium)

  1. 1. An authoritative body formally identifies the chemical as causing cancer.
  2. 2. The substantiation considered by the authoritative body meets the adequacy criteria contained in the regulations.

First Public Review Draf  

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) prepared a draft specialized support document for proposed Public Health Pretensions (PHGs) for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) in drinking water. Download the document.

PHG for PFOA and PFOS  

A PHG is the position of a drinking water adulterant at which adverse health goods aren’t anticipated to do from a continuance of exposure. As per the epidemiologic verified that operation of PFOA increases the threat of order cancer it’s associated with liver and vulnerable system toxin and increased total cholesterol, and there’s suggestive substantiation of an association with the threat of preeclampsia and gestation-related hypertension. PFOS is associated with vulnerable system toxins and increased total cholesterol in humans, with suggestive substantiation of an association with the threat of preeclampsia and gestation-related hypertension.

The specialized support document presents the scientific information available on the toxin of PFOA and PFOS, and the computation of the proposed PHGs. Please table below shows the cure responses for PFOA and PFOS, proposed by PHG and Health defensive attention.

Chemical Name PHG (ppt PHG Effect(s) HPC (ppt) HPC Effect
Perfluorooctanoic acid 0.007 Kidney cancer (human data) 3 Increased risk of liver damage (human data)
Perfluoro octane sulfonic aci 1 Cancer (animal data) 2 Increased total cholesterol (human data)

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