The Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the execution of California Proposition65(Prop65). The Carcinogen Identification Committee (CIC) of OEHHA’s Science Advisory Board serves as the state’s qualified experts and renders an opinion about whether a chemical has been clearly shown to cause cancer and the chemicals are identified as carcinogens by the CIC to be added to the Prop65 list.

OEHHA has carefully chosen perfluorooctane sulfonate (PFOS) and its salts and transformation and degradation precursors for the CIC’s review for possible listing under Prop65. By this notice, OEHHA is allowing the public to provide information relevant to the assessment of the evidence of carcinogenicity for this chemical. Relevant information includes but is not limited to:

• Transformation and/or degradation precursors of PFOS

• Cancer bioassays

• Cancer epidemiological studies

• Genotoxicity testing

• Pharmacokinetics

• Biochemical and physiological processes

The periodical of this notice marks the start of a 45-day data call-in period, ending on Monday, May 10, 2021. The evidence received during this period will be evaluated and considered by OEHHA as it plans the cancer hazard identification materials on this chemical.

Hazard identification materials will be made available to the public for comment before the CIC considers the chemical for possible listing. The openness of hazard identification materials will be published in the California Regulatory Notice Register and on OEHHA’s website. Public comments received on these materials will be sent to the CIC for its consideration before the meeting at which this chemical will be considered for listing.


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